Pilot Observation on Possible Ameliorative Effects of Aqueous Extracts from Bark of Alstonia Scholaris on Bleomycin Induced Chromosomal Damage in in Vitro Cultured Human Lymphocytes
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چکیده
In present study possible ameliorative efficacy of aqueous extract of bark of Alstonia scholaris (ASE) in cultured human lymphocytes against Bleomycin-induced cytogenetic alterations has been reported. Cultures were treated either alone with Alstonia scholaris aqueous bark extract (50μg/ml) or in combination with radiomimetic drug Bleomycin (15μg/ml). Positive implications about radioprotective effects by Alstonia scholaris bark extract on Bleomycin induced cytogenetic alteration in the form of chromosomal aberrations in in vitro human lymphocyte culture was recorded.
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